Sulfur based antibiotic
Treatment & Prevention of Pneuomocystic jivoreci
Treatment of norcadiasis
Use in AECB
Prevention of opportunistic infections in immuno-compromised patients.
Treatment of Toxoplasmosis.
Dosage: Adults: 960mg - 2.88g daily in 2 divided doses depending on severity of disease.
Children: 8mg/kg body weight daily in 2 divide doses
NB// Higher doses of 120mg/Kg body weght daily given in 2 - 4 divided doses for 14 - 21 days in treatment of Pneumocystis Carinii Jivoreci.
Prophylasxis of PCP: 960mg PO daily and may be reduced to 480mg daily to improve tolerance or 960mg daily on alternate days.
Children: 6weeks - 5 months: 120mg BD for 3 consecutive days or 7 days per week.
6 months - 5 Yrs: 240mg
6yrs - 12 yrs: 480mg
Side Effects: GIT disturbances, nausea & vomiting; Kernicterus in new borns; skin rash.